Wer hat erfolgreich einen Exploration Grant beantragt?

Im Folgenden sind die Geförderten mit den Institutionen genannt, an denen sie zum Zeitpunkt ihrer Antragstellung forschten.

2023

• Johannes Broichhagen – Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin
  "Selective protein labelling with synthetic molecules engaging in minimal tag size“
• Jan Meisner – Universität Düsseldorf
  “Computational investigation of surface-catalyzed origins of life”
• Alexandra Stolz – Goethe-Universität Frankfurt
  „Identification of small molecules for modulation of selective autophagy"
• Jakob Franke – Leibniz Universität Hannover
  “CLOGS: Development of CRISPR-based localized gene silencing in plants”
• Johannes Brendel – Universität Jena
  „Injectable supramolecular polymer fiber networks as artificial cell scaffold”
• Mark Gresnigt – Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V., Hans Knöll-Institut, Jena
  „Deciphering macrophage cell death induced by the fungal hyphal morphology and how this sacrifice directs antifungal defense“
• Andreas Gruber – Universität Konstanz
  „Exploiting gene expression changes to pinpoint disease-associated genomic variants using REACTIVE”
• Alexander Soutschek – Ludwig-Maximilians-Universität (LMU) München
  „Modulating neural representations of subjective value with temporal inference stimulation“
• Oliver Thorn-Seshold – Ludwig-Maximilians-Universität (LMU) München
  “Superfluorophores: high-performance fluorophores for single molecule superresolution imaging”
• Jan Philipp Wagner – Universität Tübingen
  „Radical mediated activation of molecular hydrogen: Application towards prebiotic carbohydrate formation”

2022

• Maike Frye – Universitätsklinikum Hamburg-Eppendorf (UKE)
  "Novel biosensor tools to study the interplay of matrix stiffness changes and endothelial function in vascular disease"
• Terrance Hadlington –  Technische Universität München (TUM)
  "Accessing Poly-DiPhospene networks as inorganic conjugated polymers for catalysis and drug delivery"
• Müge Kasanmascheff – Technische Universität Dortmund
  "Development of a small, rigid and photoactivable spin label for in cell studies"
• Hajo Kries – Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie, Jena
  "Cas9-mRNA display as a new tool for building DNA-templated enzyme cascades (CASPLAY)"
• Christian Roßner – Leibniz-Institut für Polymerforschung Dresden e.V.
  "Toward point-of-action diagnostics: Consistent colorimetric biosensing with plasmonic nanoparticles"
• Bernd Schmidt – Universität Düsseldorf
  "Catalytic modifications in a supramolecular nanocage and interplay with molecular glue"
• Peter 't Hart – Max-Planck-Institut für Molekulare Physiologie, Dortmund
  "Dithiolane modified cyclic peptides with intrinsic cell permeability"
• Christopher Teskey – RWTH Aachen
  "Expedient synthesis of unnatural amino acids via catalytic arene activation"
• Oliver Thorn-Seshold – Ludwig-Maximilians-Universität (LMU) München
  "High-resolution enzyme activity imaging: repurposing molecular photoswitches as diagnostic tools"
• Manuel van Gemmeren – Universität Kiel
  "Development of palladium-catalysts for the direct C(sp3)-H activation and functionalization of sulfonamides"

2021

• Matteo Bergami – Universitätsklinikum Köln
  "Synaptic innervation of organ-specific cancer cells and its role in tumor progression"
• Bork Berghoff – Universität Gießen
  "Multiple targeting of antibiotic resistance genes with synthetic small RNAs"
• Urs Braun – Zentralinstitut für Seelische Gesundheit, Mannheim
  "Recurrent neural networks as preclinical models of cognitive dysfunction"
• Dorian Didier – Universität München (LMU)
  "Enabling cross-coupling reactions via NIR-photocatalysis"
• Urs Gellrich – Universität Gießen
  "Three-dimensional coordination frameworks of Frustrated Lewis Pairs for reversible hydrogen and CO2 activation and storage"
• Thomas Grünewald – Deutsches Krebsforschungszentrum (DKFZ), Heidelberg
  "Dissecting and targeting the metaboic hallmarks of pediatric cancer"
• Alexander Hahn – Leibniz-Institut für Primatenforschung, Göttingen
  "Foamy virus host factors"
• Robert Kretschmer – Universität Jena
  "Dinuclear aluminium and gallium diyls as supports for transition metals"
• Jürgen Lassak – Universität München (LMU)
  "Genetic code expansion by Beta-amino acids"
• Christian Sindlinger – Universität Göttingen
  "Augmenting Frustrated Lewis-Pair reactivity by anti-aromaticity as a driving force"
• Tomohisa Toda – Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Dresden
  "Exploring nuclear architectural RNA in the long-term epigenetic regulation of neural identity"
• Peng Wu – Max-Planck-Institut für Molekulare Physiologie, Dortmund
  "Small molecules modulate the RNA-binding protein-mediated degradation of mRNA"

2020

• Guoliang Cui – Deutsches Krebsforschungszentrum, Heidelberg
  "Social Isolation inhibits protective immunity"
• Robert Göstl –  DWI Leibniz-Institut für interaktive Materialien e.V., Aachen
  "Nanoscale fractography of polymer nanocomposite interfaces with super-resolution microscopy"
• Lutz Greb – Universität Heidelberg
  "Supramolecular encapsulation for p-block element-mediated bond activation and catalysis in water"
• Ute Hellmich – Universität Mainz
  "Structure and function of a unique human and parasitic lysosomal TRP ion channel domain"
• Sebastian Henke – Technische Universität Dortmund
  "Ion conduction in metal-organic framework glasses - a new class of solid electrolytes"
• Christian Hering-Junghans – Leibniz-Institut für Katalyse e.V., Rostock
  "Synthetic strategies towards phospha-polyurethanes"
• Kirill Monakhov – Leibniz-Institut für Oberflächenmodifizierung e.V., Leipzig
  "Bioinspired "DNA-Polyoxometalate-on-a-surface" materials for nanoelectronic applications"

2019

• Tobias Beck – RWTH Aachen
  "Engineering rod-shaped protein containers for imaging and therapy"
• Christine Beemelmanns – Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie, Jena
  "Engineering NRP-PKS-hybrid enzymes for the production of Gamma-Amino acids and unique natural products (ENGINA)"
• Josep Cornella Costa – Max-Planck-Institut für Kohlenforschung, Mühlheim
  "Practical and direct incorporation of SF₅ into Heteroaromatics"
• Mafalda Escobar-Henriques – Universität Köln
  A novel form of ubiquitin controlling protein homeostasis and stress resistance"
• Matthias Feige – Technische Universität München (TUM)
  "Chemoenzymatic synthesis of highly bioactive polyketides using polyketide synthase biocatalysis"
• Inga Hänelt – Universität Frankfurt
  "Social bacteria: Fundamentals of bacterial electrical signaling by the K⁺ channel YugO"
• Frank Hahn – Universität Bayreuth
  "Chemoenzymatic synthesis of highly bioactive polyketides using polyketide synthase biocatalysis"
• Felicitas Lips – Universität Münster
  "Synthesis and reactivity of homocyclic silylenes"
• Christian Löw –  EMBL Hamburg
  "Uncovering the iron-responsive gene and protein network in malaria parasites using structural systems biology"
• Dominik Munz – Universität des Saarlandes, Saarbrücken
  "Carbenes as organic building blocks for photochemistry"

2018

• Miguel Alejandre Alcázar – Uniklinik Köln
  "Linking overactive perinatal tissue and premature pulmonary aging"
• Björn Busse – Universitätsklinikum Hamburg-Eppendorf (UKE)
  "The African turquoise Killifish (N. furzeri) as unique short-lived vertebrate model to study skeletal maturation and aging"
• Frederik Damm – Charité–Universitätsmedizin Berlin
  "Identification of patterns of phylogenetic evolution in patients with myelofibrosis"
• Ivana Fleischer – Universität Tübingen
  "Selective reduction of thioesters to aldehydes"
• Michael Giese – Universität Duisburg-Essen
  "Self-assembly in confined spaces – a tool for responsive photonic materials"
• Jesko Köhnke – Helmholtz Zentrum für Pharmazeutische Forschung Saarland, Saarbrücken
  "Natural products as inhibitors of horizontal gene transfer"
• René Königs – RWTH Aachen
  "Catalytic C-N coupling reactions with fluorinated azides"
• Steffen Lemke – Universität Heidelberg
  "Passive versus active trans-epithelial stem cell migration in flies"
• Pierre Stallforth – Leibniz-Insitut für Naturstoff-Forschung und Infektionsbiologie, Jena
  "Identification of microbially produced amoebicides (IMPA)"
• Eike Steinmann – Universität Bochum
  "Characterization of the natural compound silvestrol as novel hepatitis E virus inhibitor (AntiHepE)"

2017

• Heiko Becker – Universitätsklinikum Freiburg
  "Molecular characterization of a subset of cells with aberrant expression of myeloid progenitor and mature T cell markers in acute myeloid leukemia"
• Christina Birkel – Technische Universität Darmstadt 
  "Wet chemical synthesis of nanoscale and magnetic ternary carbides"
• Andreas Brunschweiger – Technische Universität Dortmund
  "Towards chemoresistant genetic information"
• Christine Goffinet – Helmholtz-Zentrum für Infektionsforschung, Braunschweig
  "The interplay of Mycobacterium tuberculosis and HIV-1 in co-infected human macrophages and its impact on cell-intrinsic innate immunity"
• Philipp Heretsch – Freie Universität Berlin
  "Bioinspired syntheses of sterols via alkoxy radical fragmentations"
• Michael Hiller – Max-Planck-Institut für Physik komplexer Systeme, Dresden
  "Discovering novel genes underlying human eye disorders by comparative genomics in mammals with degenerated eyes"
• Koraljka Husnjak – Universitätsklinikum Frankfurt
  "Mass spectronomy-based approach for the identification of E3 ligase substrates" 
• Jochen Niemeyer – Universität Duisburg-Essen
  "Development of new chemosensors for detection of labile iron in live cells"
• Carsten Sachse – European Molecular Biology Laboratory (EMBL), Heidelberg
  "Higher-order molecular structure of autophagy receptor p62/SQSTM-1 by in situ cryo-EM"
• Michael Schlierf – Technische Universität Dresden
  "Structural basis of conformational misfolding of cystic fibrosis mutations in CFTR"
• Andrea Thoma-Kreß – Universitätsklinikum Erlangen 
  "A novel positive feedback loop in viral oncogenesis: Regulation of the viral tax oncoprotein by NF-kappa B"
• Dagmar Wachten – Universitätsklinikum Bonn
  "Analyzing the correlation between primary clia dysfunction - inflammation - obesity"

2016

• Melanie Brinkmann – Helmholtz-Zentrum für Infektionsforschung, Braunschweig
  "Prevention of cytomegalovirus replication by CRISPR/Cas9 genome engineering"
• Marc Erhardt – Helmholtz-Zentrum für Infektionsforschung, Braunschweig
  "Investigating the immunogenic potential of flagella for salmonella-based vaccine carriers"
• Olga Garcia Mancheño – Universität Regensburg
  "Enantioselective chiral anion-catalyzed C-H bond functionalization: a fast access to chiral heterocycles"
• Annika Guse – Universität Heidelberg
  "Cholesterol-binding proteins and dinoflagellate sterols in coral symbiosis"
• Esteban Hernandez-Vargas – Helmholtz-Zentrum für Infektionsforschung, Braunschweig
  "Underlying the mechanisms between influenza virus and bacterial coinfections (VIBA)"
• Michael Lammers – Universität Köln
  "Uncovering structure and function of a novel lysine-deacetylase class in prokaryotes and its implications for eukaryotes"
• Georg Manolikakes – Universität Frankfurt
  "Direct C-H-sulfonylation of heterocycles – a new tool for late-stage diversification of functional molecules"
• Kristen Panfilio – Universität Köln
  "The role of polyploidy in epithelial tissue development"
• Christoph Rademacher – Max-Planck-Institut für Kolloid- und Grenzflächenforschung, Potsdam
  "Fragment-based design of targeted delivery vehicles: high specificity through low affinity heteromultivalent interactions"
• Jan Siemens – Universität Heidelberg
  "Hypothalamic mechanisms mediating core body temperature regulation"
• Johannes Teichert – Technische Universität Berlin
  "Ammonia borane as recycable hydrogen source for sustainable organic reactions"
• Frauke von Versen-Höynck – Medizinische Hochschule Hannover
  "Exploring the microRNA profile of endothelial progenitor cells after preeclampsia – determining opportunities for improving cardiovascular health"

2015

• Annette Andrieu-Brunsen – Technische Universität Darmstadt
  "Charge-switchable polymer gradients in mesopores: envisioning self-sustaining, electroosmotic transport in nanofluidic pores"
• Annabelle Bertin – Bundesanstalt für Materialforschung und -prüfung & Freie Universität Berlin
  "Biologically inspired de novo approach to polymer-glass fibre composites with improved mechanical properties"
• Anne-Kathrin Classen – Ludwig-Maximilians-Universität München
  "A novel mode of chromatin regulation by JNK and JAK/STAT signalling in regeneration and cancer"
• Thomas Clavel – Technische Universität München
  "PiBac – The pig intestinal bacteriome in colorectal cancer"
• Camin Dean – European Neuroscience Institute (ENI), Göttingen
  "TRPV1-mediated innervation of OLM neurons gates information flow in the hippocampus"
• Daniel Kümmel – Universität Osnabrück
  "Structural and functional characterization of Gtr GTPase-activating  proteins in TORC1 signalling"
• Christian Reinhardt – Universitätsklinikum Köln
  "Cell cycle checkpoint inhibitors as a strategy for the treatment of BRAF-dependent malignancies"
• Ulrika Westerlind – Leibniz-Institut für Analytische Wissenschaften – ISAS e. V., Dortmund
  "Exploring the chemical biology of tyrosine O-glycosylation"

2014

• Henrik Bringmann – Max-Planck-Institut für biophysikalische Chemie, Göttingen
  "Effects of sleep on ageing using C. elegans as a model system"
• Wei Chen – Max-Delbrück-Centrum für Molekulare, Medizin Berlin
  "Full-length transcriptome characterization: synaptic neuropil versus somata"
• Viktoria Däschlein-Geßner – Universität Würzburg
  "Metallierte Ylide als neuartige Kohlenstoffbasen"
• Sylvia Erhardt – Zentrum für Molekulare Biologie Heidelberg (ZMBH)
  "Identification of an RNA-based epigenetic imprint in Drosophila melanogaster"
• Steffen Scholpp – Karlsruher Institut für Technologie (KIT)
  "Analysis of a cilia-mediated transport mechanism for Shh during thalamus development"

2013

• Dina Grohmann – Technische Universität Braunschweig
  "Protein-based scaffolding of nanostructures"
• Ilona Grunwald-Kadow – Max-Planck-Institut für Neurobiologie, Martinsried
  "Characterization of the behavioural and neuronal underpinnings of ethylene detection in flies"
• Marco Trujillo Linke – Leibniz-Institut für Pflanzenbiochemie, Halle (Saale)
  "Development of a synthetic ubiquitin modification system in bacteria to assay E2-E3 pairing"

2012

• Sebastian Arnold – Universitätsklinikum Freiburg
  "Analysis of generation, maintenance and exit of stemness states of murine trophoblast stem cells"
• Manuel Friese – Universitätsklinikum Hamburg-Eppendorf
  "Charakterisierung der funktionellen Bedeutung von Arc/Arg3.1 für die Antigenpräsentation von dentritischen Zellen"
• Christian Hedberg – Max-Planck-Institut für Molekulare Physiologie, Dortmund
  "Chemical biology of histidine N-phosphrylation"
• Gunhild Layer – Technische Universität Braunschweig
  "Biochemistry of biological methane formation: biosynthesis of cofactor F430 in methanogenic Archaea"
• Ute Lindauer – Technische Universität München
  "Optogenetische Manipulation neuronaler Netzwerkaktivität zur Untersuchung von neurovaskulärer Kopplung im Rattenmodell"
• Thomas Ott – Ludwig-Maximilians-Universität München
  "Functional plasticity of plasma membrane compartmentalization during plant immune responses"
• Stefan Raunser – Max-Planck-Institut für Molekulare Physiologie, Dortmund
  "Study of prokaryotic hopanoid transporters to understand how eukaryotic cells talk to each other"
• Jens Schwamborn – Universität Münster
  "Induction of oligodendrocyte cell fate specification through the transcription factor Prox1"

2011

• Claudia Lengerke – Medizinische Universitätsklinik Tübingen
  "Untersuchung des Transkriptionsfaktors evi-1 in der Entwicklungshämatopoese im Zebrafisch-Modell"