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Exploration Grant recipients.

Our Exploration Grants programme provides opportunities to explore unexpected observations and exciting ideas and to venture into new territory. Due to their exploratory character, such projects are by nature very risky. Only a portion of them will be followed up and many will fail. Some of them will be incubators for new ideas. It is therefore the exception, rather than the rule, that Exploration Grant projects result in publications. Yet, in the last survey, more than 40 percent of the recipients reported having continued their funded projects, and around a third of all Exploration Grants were instrumental in acquiring further third-party funding, including several of the prestigious grants awarded by the European Research Council (ERC).

Who has successfully applied for Exploration Grants?

Listed below are grantees with the institutions at which they were conducting research upon submitting their applications.

2023

  • Johannes Broichhagen – Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin
    "Selective protein labelling with synthetic molecules engaging in minimal tag size“
  • Jan Meisner – University of Düsseldorf
    “Computational investigation of surface-catalyzed origins of life”
  • Alexandra Stolz – Goethe University Frankfurt
    „Identification of small molecules for modulation of selective autophagy
  • Jakob Franke – Leibniz University Hannover
    “CLOGS: Development of CRISPR-based localized gene silencing in plants”
  • Johannes Brendel – University of Jena
    „Injectable supramolecular polymer fiber networks as artificial cell scaffold”
  • Mark Gresnigt – Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena
    „Deciphering macrophage cell death induced by the fungal hyphal morphology and how this sacrifice directs antifungal defense“
  • Andreas Gruber – University of Konstanz
    „Exploiting gene expression changes to pinpoint disease-associated genomic variants using REACTIVE”
  • Alexander Soutschek – Ludwig-Maximilians-Universität (LMU) München
    „Modulating neural representations of subjective value with temporal inference stimulation“
  • Oliver Thorn-Seshold – Ludwig-Maximilians-Universität (LMU) München
    “Superfluorophores: high-performance fluorophores for single molecule superresolution imaging”
  • Jan Philipp Wagner – University of Tübingen
    „Radical mediated activation of molecular hydrogen: Application towards prebiotic carbohydrate formation”

2022

  • Maike Frye – University Medical Center Hamburg-Eppendorf (UKE)
    "Novel biosensor tools to study the interplay of matrix stiffness changes and endothelial function in vascular disease"
  • Terrance Hadlington –  Technichal University Munich (TUM)
    "Accessing Poly-DiPhospene networks as inorganic conjugated polymers for catalysis and drug delivery"
  • Müge Kasanmascheff – Technical University of Dortmund
    "Development of a small, rigid and photoactivable spin label for in cell studies"
  • Hajo Kries – Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena
    "Cas9-mRNA display as a new tool for building DNA-templated enzyme cascades (CASPLAY)"
  • Christian Roßner – Leibniz Institute for Polymer Research, Dresden
    "Toward point-of-action diagnostics: Consistent colorimetric biosensing with plasmonic nanoparticles"
  • Bernd Schmidt – University of Düsseldorf
    "Catalytic modifications in a supramolecular nanocage and interplay with molecular glue"
  • Peter 't Hart – Max Planck Institute of Molecular Physiology, Dortmund
    "Dithiolane modified cyclic peptides with intrinsic cell permeability"
  • Christopher Teskey – RWTH Aachen
    "Expedient synthesis of unnatural amino acids via catalytic arene activation"
  • Oliver Thorn-Seshold – Ludwig-Maximilians-Universität München (LMU)
    "High-resolution enzyme activity imaging: repurposing molecular photoswitches as diagnostic tools"
  • Manuel van Gemmeren – University of Kiel
    "Development of palladium-catalysts for the direct C(sp3)-H activation and functionalization of sulfonamides"

2021

  • Matteo Bergami – University Hospital Cologne
    "Synaptic innervation of organ-specific cancer cells and its role in tumor progression"
  • Bork Berghoff –  University of Giessen
    "Multiple targeting of antibiotic resistance genes with synthetic small RNAs"
  • Urs Braun – Central Institute for Mental Health, Mannheim
    "Recurrent neural networks as preclinical models of cognitive dysfunction"
  • Dorian Didier – Ludwig-Maximilians-Universität München (LMU)
    "Enabling cross-coupling reactions via NIR-photocatalysis"
  • Urs Gellrich – University of Giessen
    "Three-dimensional coordination frameworks of Frustrated Lewis Pairs for reversible hydrogen and CO2 activation and storage"
  • Thomas Grünewald – German Cancer Research Center, Heidelberg
    "Dissecting and targeting the metaboic hallmarks of pediatric cancer"
  • Alexander Hahn – Leibniz Institute for Primate Research, Göttingen
    "Foamy virus host factors"
  • Robert Kretschmer – University of Jena
    "Dinuclear aluminium and gallium diyls as supports for transition metals"
  • Jürgen Lassak – Ludwig-Maximilians-Universität München (LMU)
    "Genetic code expansion by beta-amino acids"
  • Christian Sindlinger – University of Göttingen
    "Augmenting Frustrated Lewis-Pair reactivity by anti-aromaticity as a driving force"
  • Tomohisa Toda – Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Dresden
    "Exploring nuclear architectural RNA in the long-term epigenetic regulation of neural identity"
  • Peng Wu – Max Planck Institute of Molecular Physiology, Dortmund
    "Small molecules modulate the RNA-binding protein-mediated degradation of mRNA"

2020

  • Guoliang Cui – German Cancer Research Center, Heidelberg
    "Social Isolation inhibits protective immunity"
  • Robert Göstl –  DWI Leibniz Institute for Interactive Materials, Aachen
    "Nanoscale fractography of polymer nanocomposite interfaces with super-resolution microscopy"
  • Lutz Greb – University of Heidelberg
    "Supramolecular encapsulation for p-block element-mediated bond activation and catalysis in water"
  • Ute Hellmich – University of Mainz
    "Structure and function of a unique human and parasitic lysosomal TRP ion channel domain"
  • Sebastian Henke – Technichal University of Dortmund
    "Ion conduction in metal-organic framework glasses - a new class of solid electrolytes"
  • Christian Hering-Junghans – Leibniz Institute for Catalysis, Rostock
    "Synthetic strategies towards phospha-polyurethanes"
  • Kirill Monakhov – Leibniz Institute of Surface Engineering (IOM), Leipzig
    "Bioinspired "DNA-Polyoxometalate-on-a-surface" materials for nanoelectronic applications"

2019

  • Tobias Beck – RWTH Aachen
    "Engineering rod-shaped protein containers for imaging and therapy"
  • Christine Beemelmanns – Leibniz Institute for Natural Product Research and Infection Biology, Jena
    "Engineering NRP-PKS-hybrid enzymes for the production of Gamma-Amino acids and unique natural products (ENGINA)"
  • Josep Cornella Costa – Max-Planck-Institut für Kohlenforschung, Mühlheim
    "Practical and direct incorporation of SF5 into Heteroaromatics"
  • Mafalda Escobar-Henriques – University of Cologne
    A novel form of ubiquitin controlling protein homeostasis and stress resistance"
  • Matthias Feige – Technical University of Munich (TUM)
    "Chemoenzymatic synthesis of highly bioactive polyketides using polyketide synthase biocatalysis"
  • Inga Hänelt – Goethe University Frankfurt
    "Social bacteria: Fundamentals of bacterial electrical signaling by the K+ channel YugO"
  • Frank Hahn – University of Bayreuth
    "Chemoenzymatic synthesis of highly bioactive polyketides using polyketide synthase biocatalysis"
  • Felicitas Lips – University of Münster
    "Synthesis and reactivity of homocyclic silylenes"
  • Christian Löw –  EMBL Hamburg
    "Uncovering the iron-responsive gene and protein network in malaria parasites using structural systems biology"
  • Dominik Munz – Saarland University, Saarbrücken
    "Carbenes as organic building blocks for photochemistry"

2018

  • Miguel Alejandre Alcázar – University Hospital Cologne
    "Linking overactive perinatal adipose tissue and premature pulmonary aging"
  • Björn Busse –  University Medical Center Hamburg-Eppendorf (UKE)
    "The African turquoise Killifish (N. furzeri) as unique short-lived vertebrate model to study skeletal maturation and aging"
  • Frederik Damm – Charité – Universitätsmedizin Berlin
    "Identification of patterns of phylogenetic evolution in patients with myelofibrosis"
  • Ivana Fleischer – University of Tübingen
    "Selective reduction of thioesters to aldehydes"
  • Michael Giese – University of Duisburg-Essen
    "Self-assembly in confined spaces – a tool for responsive photonic materials"
  • Jesko Köhnke – Helmholtz Institute for Pharmaceutical Research Saarland, Saarbrücken
    "Natural products as inhibitors of horizontal gene transfer"
  • René Königs – RWTH Aachen
    "Catalytic C-N coupling reactions with fluorinated azides"
  • Steffen Lemke – University of Heidelberg
    "Passive versus active trans-epithelial stem cell migration in flies"
  • Pierre Stallforth – Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena
    "Identification of microbially produced amoebicides (IMPA)"
  • Eike Steinmann –  University of Bochum
    "Characterization of the natural compound silvestrol as novel hepatitis E virus inhibitor (AntiHepE)"